Microphthalmia-Associated Transcription Factor

A basic helix-loop-helix leucine zipper transcription factor that regulates the CELL DIFFERENTIATION and development of a variety of cell types including MELANOCYTES; OSTEOCLASTS; and RETINAL PIGMENT EPITHELIUM. Mutations in MITF protein have been associated with OSTEOPETROSIS and WAARDENBURG SYNDROME.

Also Known As:

MITF Protein; MITF Transcription Factor; Transcription Factor Microphthalmia; Microphthalmia Associated Transcription Factor; Microphthalmia, Transcription Factor; Transcription Factor, Microphthalmia-Associated

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Transcription Factors: 38804
    - Basic Helix-Loop-Helix Transcription Factors: 510
      - Basic Helix-Loop-Helix Leucine Zipper Transcription Factors: 3
        Microphthalmia-Associated Transcription Factor: 476
    - Basic-Leucine Zipper Transcription Factors: 187
      - Basic Helix-Loop-Helix Leucine Zipper Transcription Factors: 3
        Microphthalmia-Associated Transcription Factor: 476
  - DNA-Binding Proteins: 2009
    - Basic Helix-Loop-Helix Transcription Factors: 510
      - Basic Helix-Loop-Helix Leucine Zipper Transcription Factors: 3
        Microphthalmia-Associated Transcription Factor: 476
    - Basic-Leucine Zipper Transcription Factors: 187
      - Basic Helix-Loop-Helix Leucine Zipper Transcription Factors: 3
        Microphthalmia-Associated Transcription Factor: 476

Wade Huber Selected Research

Wade Huber Research Topics

Disease

Drug/Important Bio-Agent (IBA)